Walther Flemming in his 1882 work “Cell substance, nucleus and cell division.” ![]() This refers to the outcome of meiosis, where the genetic information in each new cell is halved. Mitosis is the Greek word for thread, after the thread-like chromosomes that can be seen under the microscope in dye-stained cells during cell division. Another example is Klinefelter syndrome, where XY males have an additional X chromosome. One example is Down’s syndrome, caused by trisomy 21. This can trigger miscarriage, but is occasionally tolerated. Uncontrolled mitosis occurs in cancer, where either genes that stop cell division ( tumour suppressors) are switched off, or genes that encourage cell division ( oncogenes) are overactive.Įrrors in meiosis can lead to the wrong number of chromosomes ending up in germ cells, this is called aneuploidy. What is an example of a disease caused by an error in this process? Other examples are 1-2 days in male fruit flies and ~ 24 days in human males. The process lasts 6 hours in yeast but can last more than 40 years in human females, due to a developmental hold at prophase I, until ovulation. Meiosis has various timescales in different organisms, which can be affected by several factors including temperature and environment of the organism, and the amount of nuclear DNA. The process can take over 10 hours for mammalian cells in culture, budding yeast can take ~80 minutes to complete a cell cycle, whilst bacteria can divide every 20 minutes. However, there are exceptions buddingyeast will form haploid spores under nutritional deprivation. Archaeaand bacteria do not do this, so it might be tempting to think that unicellularorganisms do not sexually reproduce. Only organisms which perform sexual reproduction. Mitosis is performed by unicellular and multicellular eukaryotes.Bacteria have their own version of mitosis called “binary fission”.This is distinct from meiosis as bacteria typically have one circular chromosome,which is not contained within a nucleus, like eukaryotic chromosomes. Two diploid cells with identical genetic information.įour haploid cells with different genetic information. Various steps in meiosis create opportunity for genetic diversity in the daughter cells. To create gametes with only one copy of the organism’s genetic information, in preparation for sexual reproduction. In a multicellular organism, the purpose can be to grow during development, or to repair or regenerate In a unicellular organism, the purpose of mitosis is to proliferate asa species. Meiosis: Overview and commonly asked questions We will also explore the research into these processes and how cell division might go awry to cause disease states such as cancer and Down’s Syndrome. This article will explore the characteristics of both kinds of cell division, shining a light on how they are similar and in which aspects they are crucially distinct. In the process of replicating themselves, cells have another choice: do they want to make an identical copy and be left with two cells? Or do they want to make four “half-copies”, in preparation for sexual reproduction, where their genetic content will be made whole again by the process of fertilisation? This choice is the choice between mitosis and meiosis. ![]() ![]() Other cells, such as neurons, will never divide again once they are terminally differentiated they are post-mitotic. In humans, tissues such as the skin and blood contain cells that are actively dividing, whilst other tissues such as fat contain cells that expand (good if you need energy for winter, bad if you are trying to fit into some expensive jeans). In order for organisms to grow, cells have two options: they must either replicate themselves to create more cells, or the cells themselves must expand in volume.
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![]() This scenario would explain the high radiation levels that have been measured in different parts of the reactor building, despite the use of air-filtering equipment that was meant to decontaminate the air and bring down radiation levels before workers entered the building on Monday to survey the situation.īanri Kaieda, head of the Ministry of Economy, Trade and Industry, told reporters that the meltdown was sufficiently serious that “it will require a review of TEPCO’s schedule for bringing the plant under control.” The revised plan is to be announced on May 17. The bad news is that TEPCO suspects that the molten fuel damaged the bottom of the reactor pressure vessel, allowing radioactive water to leak out of the pressure vessel and into the building. The good news is that there appears to have been enough water at the bottom of the reactor's pressure vessel to cool the molten fuel, given that the temperature remains relatively stable between 100 degrees C and 120 degrees C. 1 reactor building earlier this week to adjust a water gauge in the reactor vessel and other instruments the resulting data showed that the water level in the reactor vessel had fallen below the fuel rods leaving them at least partially exposed.Ī TEPCO official told the press on Thursday that its seems likely the fuel rods have at least partially melted “and fallen to the bottom of the reactor. TEPCO apparently learned about the meltdown early on Thursday. A government minister said the situation was serious enough that TEPCO's " roadmap," the schedule that aims to bring the plant to a cold shutdown in less than nine months, would have to be reviewed. 1 reactor's containment vessel-a preliminary step to installing a new cooling system for the damaged reactor-to an untimely halt. The discovery brought plans to flood the No. 1 reactor of the crippled Fukushima nuclear power plant reactor have suffered at least a partial meltdown, Tokyo Electric Power Co. For more details on how Fukushima Dai-1's nuclear reactors work and what has gone wrong so far, see our explainer. This is part of IEEE Spectrum's ongoing coverage of Japan's earthquake and nuclear emergency. Editor's Note: J ohn Boyd is an IEEE Spectrum contributor reporting from Kawasaki, Japan. Traditional and Party Modes: Dabble in the throbbingly fast-paced Traditional Mode or jostle your way through some stiff competition in Party Mode including challenges like Double Delight, Obstacle Intercourse, and Weiner Round Up. ![]() Online and Local Multiplayer for Eight: Genital Jousting is more fun with friends and can satisfy up to eight players at once! Find a few willing partners, cuddle up on the couch, and share controllers or go online to joust with anonymous players from all over the world. ![]() Come join us while we follow John in his escapades to find love. If this is something that makes you uncomfortable or sounds unappealing, please do not purchase or play Genital Jousting, or even continue reading. Yeah so I found this game and its full of dicks. And with your help, that's exactly what he'll do. He wants to show everyone his astounding rigidity. Play as John, a dick who wants to find a date for his high school reunion. At Berlin Minijam last spring, programmer Evan Greenwood (director of Free Lives, the studio behind last year’s masculine-pumped action game Broforce) set out. Multiple game modes provide a stimulating orgy of objectives: penetrate and be penetrated as fast as possible or compete in absurd, silly and sexually suggestive games and challenges. Genital Jousting began at an eight-hour game jam in which game developers are challenged to build a game from scratch in the allotted time in Berlin in 2015. A videogame that has you and your friends play as mutant penis-butt creatures trying to penetrate one another might not sound like the most empowering female experience. Das Überraschende dabei: So dämlich das klingt, aber der Penis-Protagonist hat sein. Der Frühling kommt bald, die Penisse fliegen tief und das Niveau sinkt, während wir uns wie kleine Mädchen kichernd durch den Story-Modus von Genital Jousting pimmeln. Players control a detached penis complete with testicles and an anus. Genital Jousting - Story Modus im Lets Play. Meanwhile, I’m going to get Geoff Keighley and The Game Awards on the phone and let them know they missed one.Genital Jousting is an online and local multiplayer party game about flaccid penises and wiggly anuses for up to eight players at once. It goes with out saying, this SubReddit is NSFW. This is the Subreddit for future news, information, and discussions for the game Genital Jousting. A subreddit for members of the Steam Community. If you want to see more, you can check out the new trailer below. A subreddit for (almost) anything related to games - video games, board games, card games, etc. Genital Jousting is available now on PC via Steam Early Access for $4.99 USD. This may be the weirdest and my immediat. Traditional and Party Modes: Dabble in the throbbingly fast-paced Traditional Mode or jostle your way through some stiff competition in Party Mode including challenges like Double Delight, Obstacle Intercourse, and Weiner Round Up.Ĭustomize Your Member: Genitals come in all shapes and sizes so pick your favorite color and decorate it with the most appealing outfit to customize a penis you can really get behind! We're done dicking around with game shows in Multiplayer Mayhem, time to get serious with the Genital Jousting game. If this is something that makes you uncomfortable or sounds unappealing, please do not purchase or play Genital Jousting, or even continue reading. PC Game is not an official representative nor the developer of this videogame. PC Game offers a free review and price comparison service. ![]() You control a flaccid penis in Genital Jousting, which is a real game that exists. Multiple game modes provide a stimulating orgy of objectives: penetrate and be penetrated as fast as possible or compete in absurd, silly and sexually suggestive games and challenges. Guide your male genitalia to victory against the competition in this extremely NSFW PC game. The publisher of a party game where you play as a penis is hosting an E3 briefing. Players control a detached penis complete with testicles and an anus. Genital Jousting is an online and local multiplayer party game about flaccid penises and wiggly anuses for up to eight players at once. Originally, players were able to play the title as a penis, with the goal being to penetrate one another, either offline against computer controlled giggle. So what exactly is Genital Jousting? Good question - here’s an overview from developer Free Lives (the developer behind Bro Force) itself: As you may probably could guess by now, this article is completely NSFW. Yes, Genital Jousting an online and local multiplayer party game about fighting genitalia is real, and it’s now available via Steam Early Access. Every once in awhile the gaming industry pumps out some odd games - this is one of them, and then some. Graphic design isn’t just for businesses. Once you’re happy with the final design, they’ll supply high-resolution artwork in the correct format (usually pdf), that’s ready to print. Then they’ll create your draft design(s) ready for feedback. ![]() They’ll ask you plenty of questions about your brand, your goals from the printed materials, your audience, and the printing specs. Artwork for print marketingĭo you need artwork and print design for items marketing materials like brochures, flyers, business cards, posters, or even product packaging? A freelance graphic designer can produce print-ready designs to the specifications required by a professional printer. They’ll usually provide the final image design in either JPEG or PNG. Most graphic designers will include at least one round of revisions, so don’t be afraid to provide feedback if the initial design isn’t exactly what you’re after. Then they’ll use programs like Adobe Photoshop and Adobe InDesign to develop high-quality graphics you can use online. You’ll need to brief your graphic designer on your brand guidelines, examples of the styles you like, and let them know what online channels you need graphics for. Many freelance graphic designers specialise in creating graphics for your online content, like creating memes for social media, graphics for your website, and featured images for blogs. They’ll cover a whole range of visual branding-related tasks, like brand design and logo design, and can create brand guidelines to help you create a consistent look in the future. A freelance graphic designer will discuss the vision you have for your business, along with your market, your audience, brand colours, fonts, imagery, and style preferences. Whether you’re starting a new business or your existing brand needs a bit of a refresh, it’s so important that you get on-point business branding to reach your target audience. ![]() Here’s what you can expect from some of the most common freelance graphic design services: Branding Your graphic designer can work with you on a range of design tasks from branding and artwork to social media graphics and advertising. Graphic designers can make you and your business look polished and professional. Setup Stub 44.0.exe (236 KB) from download-installer.cdn. Screen Reader: Alert Notification Bar Text: Do you want to run or save Firefox. Narrator: We can select the download link with the Enter key. Screen Reader: Main landmark Free Download Link Narrator: When the page loads, press the "L" key, which will move you by list items. o r g / e n - U S / f i r e f o x / n e w / Download FireFox Free Web Browser. You can find the link in the description of this tutorial, or type in /en-US/firefox/new/ and press Enter. But for this tutorial, we're going to enter the address directly. Narrator: There number of ways to get to the Firefox Download, but if you know use a search engine like Google, it's easier to search for it. When the program has loaded, press Alt plus D to move to the address bar. Narrator: Wait for a moment as the browser launches and loads the home page. Screen Reader: Unknown Internet Explorer - Internet Explorer. Press Enter when you hear Internet Explorer Desktop app. Narrator: When you do this, you'll be moved automatically to the item to launch the browser. Screen Reader: Internet Explorer Internet Explorer. Narrator: NVDA should already be focused in the search field. Screen Reader: Cortana Window, Search Box Edit Blank ![]() To begin press the Windows key to bring up the Start Menu. In the next tutorial however, we will be covering the basics of browsing the web using Firefox, so it will be easier to follow along if you are using the same browser. So with that in mind, Firefox is our preferred web browser to pair with NVDA, but other browsers, including Internet Explorer, may work for you as well. When using a screen reader however, there's an extra layer of complexity that some browsers don't handle very well. The internet is based on standards, so any compliant web browser should be able to provide access to content in the same way, with the only difference being peripheral features such as bookmark management. A web browser is simply a program that runs on your computer that is able to communicate with servers on the internet which present you, the User, with web pages. Narrator: In this tutorial we'll be downloading and installing the Mozilla Firefox web browser. Intro: The American Foundation for the Blind in Association with NVAccess presents:Īn Introduction to using your computer and getting online. On your device, go to Settings > General > Reset > Reset Location & Privacy 5. ![]() > General > Reinstall Mobile Device Services. If that does not fix your issue, you can reinstall Mobile Devices Services from iMazings preferences: Edit > Preferences. Chose which data sets you want to restore. The simplest way to update your Apple drivers is to install the latest version of iTunes. iMazing will start loading your photo library straight from your mobile device, and let you browse it while it's still loading thumbnails in the background. ![]() Browse and manage multiple backups of the same iOS device. Connect your iPhone, iPad or iPod touch to your computer and click the Photos icon.Browse, save, and add contacts to your iPhone, without automatically adding them to your iCloud account. iMazing Configurator is only available to enterprise organizations, and if you are interested, you can request a trial.Browse and save messages (SMS, MMS, iMessage), voicemails, and call logs, none of which iTunes can do.Features of iMazing: Transfer all the data you need to your new iPhone even without the use of iCloud or iTunes. It even lets you back up iPhone contacts, SMS, photos and playlists to computer. from iOS devices to iTunes or PC directly. Transfer files to and from an iOS device, and browse the iOS file system. Distinguishing from iTunes, iMazing allows you to add music, movies, TV shows, podcast and audiobooks, etc.Free DownloadFree DownloadFree DownloadBuy Now Supports every iPhone, iPad & iPod. Powerful and user-friendly, iMazing works on Mac and Windows. Backup & restore individual iOS apps along with your custom saved data, perfect for freeing up space on your iOS device without losing your files, great for installing apps including your data on another iOS device you own. iMazing File Transfer Browse and transfer files and documents between your iPhone and your computer.Available on both macOS and Windows PCs, the app lets you take control of your iOS data: make Time. ![]() Certain features are available for free, including the new. Music transfer done right, without limitations or restrictions. iMazing is the Swiss Army Knife of iOS device management. iMazing is a useful app for Mac and Windows that gives you a wealth of backup, transfer, and management tools for your iPhone and iPad.
![]() How to disable Multi Window on Galaxy S7 and Galaxy S7 edge?.How to use Galaxy S7 application manager?.Switch to Galaxy S7: how to migrate old phone data to Galaxy S7 and Galaxy S7 edge with Smart Switch?. ![]()
![]() If the field layout is not consistent between the DBF and the ODBC connection file, data will be misplaced causing problems during import or matching. To import ODBC data into an existing mDesktop Main File, the DBF structure of the Main File must be consistent with the fields selected in the ODBC connection. Importing ODBC Data into an Existing Main File However, starting the Setup Wizard via the Single File or Two File button will allow you to specify an ODBC Connection file or create a new one, as discussed in "Creating an ODBC Connection file". Choosing the latter method will prompt you for the file that you wish to import, so you can only use this if you have previously created an ODBC Connection (*.ODB) file. The mDesktop Setup Wizard can be launched by selecting one of the file wizards or by selecting the Setup Wizard option located under the Import menu. Using mDesktop's Setup Wizard to Import ODBC Data Once you have created an ODBC Connection file, you can import the data selected via mDesktop's Setup Wizard or by importing it into an existing mDesktop Main File. You can select fields individually by double-clicking, select a block of fields by highlighting them and clicking "Add", or use the Add All button. This feature can help improve processing time by limiting the size of large files with numerous fields that are unrelated to the matching process, as well as reducing the setup time required in mDesktop. When importing a table or view, you can choose what fields you would like to import. This defines the data that will be imported. Selecting a TableĪfter choosing a data source, select a table or view from the drop-down list of available tables. If prompted, enter the Login ID and Password for the data source. To choose an ODBC Data Source, click the button. The ODBC Connection Manager window is then displayed as follows. You can create an ODBC Connection file by selecting the ODBC Connection Manager option from the File menu or by choosing the ODBC option in the mDesktop Import Manager window, as shown below (to access the ODBC Connection Manager window - click "…" after choosing the ODBC radio button). The following sections explain mDesktop's ODBC functionality in detail, covering all of the major options and processes. On output, the user can choose to create a new table, overwrite an existing table, or delete records from within a table and reassign orphaned records in a child table. mDesktop uses an ODBC Connection file to import the required information from the chosen data source, as well as export data back to the original source database. The user can select which fields from the table or view they would like to import. When importing data, the user must create a single table or view containing the data which is to be read into mDesktop – for Access, this can be a query. Supported ODBC drivers include the standard ones for SQL Server, mySQL, DB2, Oracle and Access. MDesktop can read and export data using standard ODBC connections. ![]() They can be accessed using special URL who ends with. The most famous part of the dark web are the hidden services built on the tor network. You’ll need to use a particular application or a special proxy. The Dark Web is a part of the web that you cannot access using a regular browser.The Deep Web is a part of the web non indexed, It means that you cannot find these websites using a search engine but you’ll need to access them by knowing the associated URL / IP address.It’s indexed by popular web crawler such as Google, Qwant, Duckduckgo, etc… The Surface Web, or Clear Web is the part that we browse everyday.The web is composed of 3 layers and we can think of it like an iceberg: I won’t be too technical to describe what the dark web is, since it may need is own article. What I wanted to do this time was to build a web crawler for the dark web. ![]() So I didn’t wanted to make a new one again. You may know that there is several successful web crawler running on the web such as google bot. The weakest link determines the strength of the whole chain. To be efficient, a distributed web crawler has to be well designed: it is important to eliminate as many bottlenecks as possible: as french admiral Olivier Lajous has said: Typically a efficient web crawler is designed to be distributed: instead of a single program that runs on a dedicated server, it’s multiples instances of several programs that run on several servers (eg: on the cloud) that allows better task repartition, increased performances and increased bandwidth.īut distributed softwares does not come without drawbacks: there is factors that may add extra latency to your program and may decrease performances such as network latency, synchronization problems, poorly designed communication protocol, etc… It’s basically the technology behind the famous google search engine. I have written several one in many languages such as C++, JavaScript (Node.JS), Python, … and I love the theory behind them.īut first of all, what is a web crawler? What is a web crawler? ⌗Ī web crawler is a computer program that browse the internet to index existing pages, images, PDF, … and allow user to search them using a search engine. I have been passionated by web crawler for a long time. ![]() Some of these OXPs have tapped into the potential of the more recent graphics cards and given ships full Shader 2.0 texturing and light mapping making Oolite's graphics comparable to the current crop of space sims like Eve Online and the X series. The OXP system (Oolite eXpansion Pack) allows players/developers the chance to design and include content into the main game, whether it be a new ship, new missions or even new planets. The graphics engine makes full use of the functionality of OpenGL and the AI is much more advanced than original Elite - where the latter was player-centric (action was centered around the player) Oolite has an ever-changing and independent universe centered around the planet being visited. Oolite takes Elite and basically gives it a makeover. It is popular with its players due to staying true to the gameplay and atmosphere of the original but adding a more dynamic universe and the ability to create new content for the game. Oolite is one of the few Elite-related projects to have survived and created a noteworthy product. It was originally developed for MacOS but was converted to Linux and Win32 formats. However, the 32-bit version should run on 64-bit Windows without issues as well.Oolite is a clone of Elite, created and developed since the early 2000s by Giles "aegidian" Williams until he stepped down as a developer and was replaced by a small team of developers led by Jens "Ahruman" Ayton". They are the recommended ones for 64-bit OSes. oxp folder into AddOns.Ħ4-bit builds of Oolite for Windows are available and the development environment used defaults to 64-bit executables generation. ![]() NB: most OXPs zip files contain a folder with a README file and the actual OXP directory (somename.oxp) as a sub-folder - in this case, it's best to unzip the OXP somewhere else and then copy the unpacked. Create an AddOns folder beside the oolite.app folder. You will need to find where the oolite.app folder is placed: versions 1.65 to 1.72.x should default to C:\Program Files\Oolite, later versions default install is C:\Oolite, to avoid clashes with Vista's virtual folders feature(see above). If your game seems to have unreasonably low fps performance (check this in-game by hitting SHIFT-F) it is strongly recommended you visit your graphic cards' suppliers website and download and install the latest drivers. Note that the following key combination will get you out of 'graphics related trouble': Alternatively double click the Oolite program icon on the desktop. Use Windows Explorer to search for the string " *.oolite-save " with the Windows search option " include system and hidden files" checked (turned on).įor example, the default commander, if saved, might be found in this path:Ĭ:\Users\\AppData\Local\VirtualStore\Program Files\Oolite\oolite.app\oolite-saves\Jameson.oolite-saveįind the Oolite icon in the Start -> Programs menu and click on it.Examine location C:\Users\\AppData\Local\VirtualStore\Program Files\Oolite\oolite.app\oolite-saves\.If you have already installed Oolite on a Vista machine and wish to move your saved games to a new and safer file location: Recovering Your Commanders Saved Under Vista You can read more about this problem on this Oolite forum thread. This is because Vista virtualizes files in those locations for legacy processes. Vista rearranges some files outside the Oolite folder structure without visible alias/redirects, which completely hides all saved games and causes some OXP add-ons to malfunction. It is STRONGLY recommended NOT to use the folder C:\Program Files\Oolite\ or any path including the following: When asked by the installer, change the Oolite install directory to a different location, one outside C:\Program Files\, like Oolite 1.73 and later releases have corrected this issue by using a different default installation directory, instead of one inside program files, as before. Important note for Vista users! Summary:ĭATA LOSS and OXP MALFUNCTION can appear if you install an early version of Oolite (1.65 - 1.72.x) on Vista. It will not run on the DOS-extender versions of Windows such as Windows 95, 98 or ME.įor Windows XP, the last version compatible with the OS is 1.84. This game uses OpenGL, and you are advised to run the latest 3D graphics drivers from your 3D card manufacturer. The game has been tested on Windows Vista SP2, 7, 8, 8.1 and 10. To install, run the installer that you have just downloaded. The latest recommended release, 1.90 can be downloaded from. To be added by someone with the right knowledge. Note that this page is referenced as 'Building' from however this page does not contain any build information. The Windows port of Oolite is built from the same source as the Mac OS X and Linux versions, and has all the features of those versions.Īll OXPs should be compatible with the Windows port. 3.1.5 Recovering Your Commanders Saved Under Vista.3 Getting and installing the compiled game. |
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